Title

Chronic Outcomes in Interhemispheric Transfer Time Among Children With Moderate to Severe Traumatic Brain Injury

Publication Date

5-2016

Abstract

Traumatic brain injury (TBI) frequently results in diffuse axonal injury and other white matter damage. The corpus callosum (CC) is particularly vulnerable to injury following TBI, though the impact of this damage may not be apparent until several months to years following injury. Damage to the CC has been associated with impaired neurocognitive functioning in children with TBI. Event-related potentials were used in this study to measure interhemispheric transfer time (IHTT) as an indicator of CC integrity in 31 youth with moderate/severe TBI (msTBI) at the chronic phase of recovery (i.e., 13-18 months post injury), compared with 22 healthy control youth. Neurocognitive performance was also examined among these groups. At the chronic phase of recovery, TBI group youth overall demonstrated slower IHTTs and worse neurocognitive functioning than youth in the control group. Only a subset of msTBI group children had IHTTs that were outside the range of the healthy controls; however, this impairment in interhemispheric communication was not significantly linked with neurocognitive test performance. Overall, this study demonstrated that msTBI results in longstanding differences in interhemispheric and neurocognitive functioning, but injured children are differentially impacted. For future studies, investigators might examine explanatory mechanisms for differential outcomes following msTBI, including corresponding structural and metabolic changes using advanced imaging techniques.

First Advisor

Marion, Sarah DeBoard

Date Uploaded

10-12-2018

Collection Number

Psych0371E

Document Type

Dissertation

File Name

Ellis_fuller.psych_0371E_10166

Language

English

Keywords

Brain damage, Neural circuitry, Neurophysiology, Cerebral dominance, Corpus callosum

Disciplines

Psychology

Rights

Material hosted by ProQuest subject to copyright

Comments

This was uploaded by the David Allan Hubbard Library from the ProQuest Dissertations and Theses (ProQuest). If there are any mistakes in this record, please contact archives@fuller.edu.

ProQuest URL

https://search.proquest.com/docview/1895145352/504E9523FCEA4FFBPQ/1?accountid=11008

Upload File

wf_no

Embargo Period

10-12-2018

Share

COinS